1,8-Naphthalic Anhydride

    • Product Name: 1,8-Naphthalic Anhydride
    • Chemical Name (IUPAC): Naphthalene-1,8-dicarboxylic anhydride
    • CAS No.: 81-84-5
    • Chemical Formula: C12H6O3
    • Form/Physical State: Solid
    • Factroy Site: No. 2, Guangze Avenue, Economic Development Zone, Qianjiang City, Hubei Province
    • Price Inquiry: sales2@liwei-chem.com
    • Manufacturer: Qianjiang Yongan Pharmaceutical Co., Ltd.
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    Specifications

    HS Code

    934157

    Cas Number 81-80-1
    Iupac Name 1,8-Naphthalic anhydride
    Molecular Formula C12H6O3
    Molar Mass 198.18 g/mol
    Appearance White to yellowish crystalline powder
    Melting Point 273-276 °C
    Boiling Point Decomposes before boiling
    Solubility In Water Insoluble
    Density 1.52 g/cm³
    Refractive Index 1.688
    Flash Point >200 °C
    Synonyms 1,8-Naphthalenedicarboxylic anhydride
    Odor Odorless
    Storage Temperature Store at room temperature, dry and tightly closed
    Pubchem Cid 7342

    As an accredited 1,8-Naphthalic Anhydride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Application of 1,8-Naphthalic Anhydride

    Purity 99%: 1,8-Naphthalic Anhydride with 99% purity is used in pharmaceutical intermediate synthesis, where it ensures high yield and product consistency.

    Melting Point 273°C: 1,8-Naphthalic Anhydride with a melting point of 273°C is used in high-temperature pigment manufacturing, where it maintains process stability.

    Particle Size <10 µm: 1,8-Naphthalic Anhydride with particle size below 10 µm is used in specialty coatings, where it enhances dispersion and film uniformity.

    Stability Temperature 200°C: 1,8-Naphthalic Anhydride stable up to 200°C is used in polymer modification, where it retains chemical integrity during compounding.

    Molecular Weight 198.17 g/mol: 1,8-Naphthalic Anhydride with molecular weight of 198.17 g/mol is used in organic electronics, where it provides predictable reactivity in material design.

    Low Moisture Content <0.2%: 1,8-Naphthalic Anhydride with moisture content below 0.2% is used in agrochemical formulations, where it minimizes hydrolysis risk.

    High Assay ≥99.5%: 1,8-Naphthalic Anhydride with assay of at least 99.5% is used in dye synthesis, where it delivers consistent chromophore quality.

    Recrystallized Grade: 1,8-Naphthalic Anhydride of recrystallized grade is used in laboratory research, where it supports reliable experimental reproducibility.

    Low Impurity Level <0.1%: 1,8-Naphthalic Anhydride with impurity level below 0.1% is used in optoelectronic materials, where it prevents device degradation.

    Fine Powder Form: 1,8-Naphthalic Anhydride in fine powder form is used in advanced composite materials, where it improves matrix compatibility and dispersion.

    Packing & Storage
    Packing 1,8-Naphthalic Anhydride is supplied in a 500g amber glass bottle, securely sealed with a screw cap and a safety label.
    Container Loading (20′ FCL) Container Loading (20′ FCL): 11 metric tons of 1,8-Naphthalic Anhydride packed in 25 kg bags, 440 bags per container.
    Shipping **Shipping Description for 1,8-Naphthalic Anhydride:** Pack in tightly sealed containers, away from moisture and incompatible substances. Store in a cool, dry, well-ventilated area. Handle with care to prevent spillage. Transport according to local and international regulations for chemicals; label containers with proper hazard information. Use personal protective equipment during handling and shipping.
    Storage 1,8-Naphthalic Anhydride should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from moisture, heat, and direct sunlight. Keep it separated from strong oxidizing agents and bases. Store at room temperature and ensure good labeling and safety signage. Use proper PPE when handling, and avoid inhalation of dust or contact with skin and eyes.
    Shelf Life 1,8-Naphthalic Anhydride typically has a shelf life of 2-3 years when stored in a cool, dry, and tightly sealed container.
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    More Introduction

    1,8-Naphthalic Anhydride: Direct from the Manufacturer’s Perspective

    Decades of Experience with 1,8-Naphthalic Anhydride

    From inside the factory, the story of 1,8-Naphthalic Anhydride is shaped by years of practical chemistry, precise control of reaction conditions, and a steady response to the evolving requirements of real-world industries. Each batch reflects decisions made by chemists who have watched both market and regulatory trends, adjusting our approach as customer expectations and environmental concerns develop. The value of this chemical goes far beyond its CAS number and melting point; it stands as a critical intermediate, built with hands-on expertise and process optimization gathered through sustained production, scale-up trials, and customer feedback on application outcomes.

    Physical Qualities and Production Realities

    1,8-Naphthalic Anhydride isn’t something pulled out of thin air. Our production method relies on refined oxidation of 1,8-naphthalene dicarboxylic acid at controlled temperatures, ensuring a high-purity white to off-white crystalline powder. Moisture content, residual acid, color, and particle distribution are all measured and tightly managed. Quality isn’t about a checklist. The control over off-odors, clumping, and trace impurities gets forged through repeated pilot runs and small shifts in raw material sources.

    Model designations like “NA8” or “Tech Grade NA” usually speak to user familiarity rather than any trade gimmick — these originate from direct feedback between process engineers and long-time users in dye synthesis, plastics, and pigment manufacture. If the process needed to switch solvent systems or handle heat transfer differently, these subtle product changes matter far more to daily users than the theoretical properties described in academic papers.

    Usage Rooted in Practice, Not Theory

    Most of our naphthalic anhydride ends up in colorant chemistry: synthesis of N-alkyl and N-aryl naphthalimide dyes. These dyes show intense fluorescence, high migration resistance, and chemical stability, making them favorites in fields like tracing agents, optical brighteners, and robust color pigments for thermoplastics and textiles. These aren’t hypothetical uses. They come from thousands of hours of hands-on collaboration, troubleshooting solubility and reactivity at real production scales.

    Some customers turn to this anhydride as an intermediate in pharmaceutical research, especially for heterocyclic compounds targeting anti-inflammatory or anti-cancer applications. While only a small share goes into pharma labs, these customers value crystal clarity, batch-to-batch repeatability, and the ability to meet tricky analytical standards. Each industrial sector leaves its own fingerprint, which means we get a daily reminder that small manufacturing tweaks can have far-reaching consequences in downstream performance.

    What Sets 1,8-Naphthalic Anhydride Apart from Similar Products

    We’ve worked with both isomers of naphthalic anhydride — 1,8 and 2,3. Although they may sound interchangeable, the two bring different dimensionality to chemical synthesis. 1,8-Naphthalic Anhydride creates naphthalimide scaffolds with high rigidity and a planar structure; this gives finished dyes a deeper hue and improved photostability. In comparison, 2,3-Naphthalic Anhydride can create brightness, but customers needing lightfastness and strong molecular stacking consistently return to 1,8 because of its proven reliability.

    Some new entrants in the market may try substituting phthalic anhydride, hoping to lower costs. We’ve seen first-hand the drop-off this brings in dye purity, especially in applications demanding complex ring closures, such as fluorescent markers and advanced pigment systems. 1,8-Naphthalic Anhydride’s unique reactivity, derived from the peri-positioned anhydride, shapes the geometry of the naphthalimide core and opens reaction pathways closed to similar-looking intermediates. This is no academic distinction. Customers facing failed curing, poor fluorescence, or unpredictable shades often track these issues back to a switch from 1,8 to non-peri isomers or unrelated anhydrides.

    Specifications become more than numbers on a certificate — they’re the result of countless conversations with plant managers, supply chain partners, and end-users tackling tough production standards. Purity routinely exceeds 99 percent by HPLC, and our staff monitor color (APHA values), particle size, and acid value as part of the daily routine. These specs aren’t dreamed up in isolation; they evolve based on what works in high-throughput synthesis, large dye kettles, and modern plastics compounding. When competitors try to match our metrics by taking shortcuts (shaving time off crystallization or neglecting fine particulates), we’ve seen end-users run into trouble with filterability or unexpected side-products.

    Meeting Environmental and Regulatory Pressures

    Nobody in chemical manufacturing gets by with high-aniline residues or incomplete dehydration anymore. We’ve adapted our process to pre-wash crude product with high-purity solvents and operate under closed systems, both for better worker safety and to keep our product within strict regulatory targets. We learned that regulatory trends — from Europe’s REACH to changing Chinese export certifications — directly alter the micro-decisions on the plant floor: how much to invest in distillation recovery, how tightly to monitor byproducts, and how to respond to local community concerns about air emissions.

    Sustainable production means choosing feedstocks from vetted suppliers, keeping wastewater generation to an absolute minimum, and monitoring for volatile organics well below published occupational limits. Downstream customers increasingly demand supply chain traceability, and this is something we implement not out of obligation, but because lapses can blow back directly to our plant — sometimes with legal or commercial consequences. Clean-up and emission reduction shape ore selection, catalyst preference, and the selection of plant-site locations. Every link — from raw material sourcing to packaging and waste management — passes through hands-on assessments driven by what regulatory bodies and, ultimately, our clients expect from a modern chemical company.

    Real-World Feedback, Not Hype

    Sharpshooters in the colorants industry recognize that just a few percent higher purity and improved filtration characteristics can mean massive differences downstream. We’ve seen pigment makers hit yield bottlenecks or lose product quality due to excessive fines or residual acid. Adjusting our drying and grinding parameters, or introducing a post-purification step, traces directly to these feedback cycles. Customers reach out not for a sales pitch, but for insight on risk factors: moisture absorption, storage stability, and resistance to caking during seasonal temperature swings.

    Most resellers and traders skim over these details. As a producer, we see the small-scale trials, the failed reactions, and the points where real-world customers catch what the spec sheets miss. End-users depend on us not to hide or gloss over such information. Lab managers request batch samples because not every pressing or reaction cycle behaves identically; time spent on technical support or joint R&D collaborations makes up a big part of our role.

    Responsibility and Transparency in Chemical Manufacturing

    Years in the manufacturing business teach you that transparency can make or break long-term customer relationships. A plant-level problem — off-grade raw material, uneven heating, or a misstep in recrystallization — can lead to catastrophic errors down the supply chain. Key account partners have walked our shop floors, seen our analysis systems in action, and audited our recordkeeping. Trust gets built through honesty about setbacks, precision in documentation, and clear communication when supplies get tight or quality needs rechecking.

    Meeting the needs of technical customers for 1,8-Naphthalic Anhydride means going beyond shipping product. We support clients who require LLQC (lot-lot quality consistency), who want granular data on IR, NMR, or MS spectra, or who bring batch-specific questions about impurities (chlorinated or sulfur-containing byproducts, for example). Where possible, we maintain a reserve stock for repeat lots because a switch in crystalline form can derail scale-up or formulation trials.

    How the Manufacturing Process Impacts the Final Product

    Every shift in equipment calibration or process control finds its way into the bottle or drum sent out. Years of producing 1,8-Naphthalic Anhydride have shown that customers value process repeatability — how the product behaves in their processes, not just its nominal purity. We track the variables that matter: drying time, grinding methods, solvent recovery, and filtration speed. A change in pH during the washing step or an hour’s deviation on dehydration can cause issues for downstream users. This direct knowledge, drawn from our own production lines, sets honest expectations: trace chloride or metals, slight changes in color, or lot-specific differences are not abstract concepts but everyday realities for users.

    Relaying this information up front helps users plan for possible hiccups in formulations or quality control. We maintain ongoing dialogue with frequent buyers, helping them optimize their own processes based on real manufacturing realities faced on our side. Open, two-way communication gives both sides leverage to overcome technical or commercial obstacles.

    Bulk Supply, Storage, and Handling: Real Challenges

    Big-volume production comes with direct lessons learned. Under humid conditions, 1,8-Naphthalic Anhydride can absorb atmospheric moisture, clump, or hydrolyze at the edges of bags. To address these risks, we warehouse finished goods under controlled conditions and partner with logistics providers who understand the sensitivity of high-value organic intermediates. Lessons learned from past mishaps — accidental exposure to wet handling or compromised secondary packaging — push us to invest in moisture-barrier bags, desiccant packs, and sealed drums.

    Storing intermediate inventories above or below room temperature becomes a balancing act. Longer dwell times mean more risk of lumpy or fused crystals, so we manage turnover cycles and prevent exposure to temperature extremes. Our internal quality teams sample retained lots for caking and purity drift, sharing this data with local buyers seeking transparency and assurance before committing to new orders.

    Listening to Evolving Customer Needs

    Relying on user experience — not just catalog specs — shapes our continuous upgrades. International dye manufacturers shifted toward lower residual solvents to meet tougher export standards. Plastics processors called for higher flowability to fit automated dosing. We didn’t anticipate all these requirements out of the gate; feedback from technical users, process engineers, and research partners keyed us in. The flexibility to adapt — whether in granule sizing, custom packaging, or batch labeling — keeps the cycle of quality improvement alive.

    Some buyers in the advanced materials space request enhanced traceability, building a bridge between the chemical’s factory origins and global end-use certifications. Documentation demands, including detailed COAs and trace impurity analysis, carry increasing importance. Our plant teams handle requests for tailored drying, inert gas blanketing, or specific drum loading as a matter of course, trained by repeated experience.

    Applications Extend Beyond Dyes and Pigments

    A growing number of researchers look to 1,8-Naphthalic Anhydride in the development of semiconductors and optoelectronic devices. Experiments show that unique conjugation and ring structure promote photoluminescence, making it a material of choice in exploratory studies of organic transistors, fluorescent sensors, or photoactive polymers. Most of this usage takes place in small volumes, but feedback from the research community influences our approach to impurity monitoring and sample dispatch.

    Materials science departments sometimes need micro-batches — not freight consignment — and we try to turn these micro-interactions into learning moments for the wider production team. Shifts in surface area, crystallite size, or residual solvent can make or break a new application. Listening carefully to this feedback forms a loop of practical improvement, with our R&D and QC teams sharing insights and implementing incremental upgrades.

    Practical Considerations: Shipping and Safety

    As a manufacturer, we take matters of shipping integrity and safety personally. Tightly sealed packaging and accurate labeling form the foundation of every shipment, but years of real-world logistics have shown just how unpredictable transport can be — from marine humidity shifts to warehouse mishandling. Our logistics teams select routes based on weather, transit times, and the reputations of local freight handlers.

    Workers involved in packing and quality inspection understand the reactivity risks posed by impure or mishandled product. Training, workplace safety culture, and on-site response capabilities all grew alongside our commitment to high-purity 1,8-Naphthalic Anhydride. This experience translates directly to lower risk for our customers and ensures regulatory compliance on both sides of the border.

    Comparing Direct Manufacture to Third-Party Supply

    Most distributors relay what they’re told; as manufacturers, we see the micro-decisions playing out at every stage. The dialogue with users and process specialists keeps us honest; flaws and failures reach us back almost as quickly as successes. We stay vigilant against batch-mixing mistakes or shipping delays because customer operations depend on tight, predictable supply. The stream of practical questions — drum sizes, handling tools, temperature tolerance, lot-to-lot variation — keeps our attention on the results that matter, not just the specs.

    That same focus means a refusal to cut corners: no substandard packaging, no recycled drums for direct contact, no blended lots presented as single-source material. The market responds; repeat buyers notice these differences and build their supply chains around reliability achieved by careful sourcing, process discipline, and transparent records.

    Long-Term Perspective: More Than a Commodity

    1,8-Naphthalic Anhydride sits at the core of projects that drive both incremental industrial innovation and striking breakthroughs. We don’t treat it as a generic commodity but as a foundation for colorants, plastics, electronics, and lab research that will keep evolving. Growing demand for custom applications will keep pushing our plant to adapt and refine what we produce.

    This adaptability is only possible with consistent, reciprocal communication among technicians, buyers, regulatory authorities, and our own team. Our everyday reality — tuning reactors, overseeing purification, and resolving technical support questions — means we live the supply, we don’t just document it. We take pride in every drum or small batch that leaves our warehouse, knowing its success travels far beyond numbers on a spec sheet.

    Factory experience and close partnerships across the value chain have shown us that rigorous production of 1,8-Naphthalic Anhydride isn’t just about chemical benchmarks. It’s about honest reliability, readiness to support new requirements, and direct engagement with everyone who depends on a stable, well-characterized supply. That’s the reality we work hard to maintain, every batch, every shipment, every time.